Valeriana
Contenuto
Titolo
Valeriana
Descrizione
Valeriana officinalis L.
FAMIGLIA: Valerianaceae
PRINCIPI ATTIVI: olio essenziale (0,2-2,8%): monoterpeni: acetato di bornile, acetato di mirtenile, camfene, pineni ecc.; sesquiterpeni non volatili (acidi carbassilici ciclopentanici): acido valerenico, acido acetossivalerenico, acido idrossivalerenico; sesquiterpenivolatili: valeranale, valerianolo, valerenolo e suoi esteri, valeranone, alcol kessilico, eudesmatriene e altri carburi. Iridoidi o Valepotriati (0,8-1,7%): valtrato e isovaltrato come maggioritari (non sono idrosolubili, sono termolabili e instabili si degradano in baldrinali); alcaloidi (tracce): actinidia, naftiridilmetilcetone; acidi-fenoli; acida y-amino-butirrico; flavonoidi (6-metil-apigenolo, linarina).
La composizione dell' olio essenziale varia secondo la stagione, le condizioni di coltura e soprattutto procedimenti di ottenimento.
La concentrazione in acido valerianico e dei suoi derivati (0,2-0,7%), è massima in marzo (anche 0,9%). La radice fresca è pressoché inodore: durante l'essiccamento compare il tipico odore dovuto alla liberazione dell'acido isovalerianico.
BIBLIOGRAFIA:
- Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats.
K Murphy et al. Phytomedicine. 2010 Jul.
- Enrica Campanini "Dizionario di fitoterapia e piante medicinali".
- Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study. Harshith Chandra Shekhar et al. Adv Ther. 2024 Jan.
- Valeriana officinalis extract and its main component, valerenic acid, ameliorate D-galactose-induced reductions in memory, cell proliferation, and neuroblast differentiation by reducing corticosterone levels and lipid peroxidation. Sung Min Nam et al. Exp Gerontol. 2013 Nov.
- Neuroprotective properties of Valeriana officinalis extracts. João O Malva et al. Neurotox Res. 2004.
- A Review Focused on Molecular Mechanisms of Anxiolytic Effect of Valerina officinalis L. in Connection with Its Phytochemistry through in vitro/in vivo Studies. Ilkay E Orhan. Curr Pharm Des. 2021.
- Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. P D Leathwood et al. Pharmacol Biochem Behav. 1982 Jul.
- Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis. Noriko Shinjyo et al. J Evid Based Integr Med. 2020 Jan-Dec.
- The influence of standardized Valeriana officinalis extract on the CYP3A1 gene expression by nuclear receptors in in vivo model. Anna Bogacz et al. Biomed Res Int. 2014.
- Valeriana officinalis root extract suppresses physical stress by electric shock and psychological stress by nociceptive stimulation-evoked responses by decreasing the ratio of monoamine neurotransmitters to their metabolites. Hyo Young Jung et al. BMC Complement Altern Med. 2014.
- Optimizing the extract yield of bioactive compounds in Valeriana officinalis root: a D-optimal design. Arash Mokhtari et al. Prep Biochem Biotechnol. 2024.
- Effects of Valeriana officinalis (Valerian) on tension-type headache: A randomized, placebo-controlled, double-blind clinical trial. Hossein Azizi et al. Avicenna J Phytomed. 2020 May-Jun.
- Intraspecific Variability of Wild-Growing Common Valerian (Valeriana officinalis L.). Katarzyna Barbara Bączek et al. Plants (Basel). 2022.
- Identification of Nrf2 Activators from the Roots of Valeriana officinalis. Sualiha Afzal et al. Planta Med. 2023 Jan.
- Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [H]Glutamate Binding to Rat Synaptic Membranes. Lisa M Del Valle-Mojica et al. Evid Based Complement Alternat Med. 2011.
- Valeriana officinalis extract and 7-Nitroindozole ameliorated seizure behaviours, and 7-Nitroindozole reduced blood pressure and ECG parameters in pentylenetetrazole-kindled rats. A Kapucu et al. Pol J Vet Sci. 2020 Sep.
- Valeriana officinalis Dry Plant Extract for Direct Compression: Preparation and Characterization. Loreana Gallo et al. Sci Pharm. 2012 Oct-Dec.
- The potential of Valeriana as a traditional Chinese medicine: traditional clinical applications, bioactivities, and phytochemistry. Jianchun Li, Xiaoliang Li, Changfu Wang, Manli Zhang, Minhui Ye, Qiuhong Wang.
- Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties.
Miguel Hattesohl et al. Phytomedicine. 2008 Jan.
- NF-kappaB modulators from Valeriana officinalis. Nadia J Jacobo-Herrera et al. Phytother Res. 2006 Oct.
- Biological and analytical characterization of two extracts from Valeriana officinalis. Clara Circosta et al. J Ethnopharmacol. 2007.
© Copyright Associazione capra&cavoli, condividi non copiare. Grazie
FAMIGLIA: Valerianaceae
PRINCIPI ATTIVI: olio essenziale (0,2-2,8%): monoterpeni: acetato di bornile, acetato di mirtenile, camfene, pineni ecc.; sesquiterpeni non volatili (acidi carbassilici ciclopentanici): acido valerenico, acido acetossivalerenico, acido idrossivalerenico; sesquiterpenivolatili: valeranale, valerianolo, valerenolo e suoi esteri, valeranone, alcol kessilico, eudesmatriene e altri carburi. Iridoidi o Valepotriati (0,8-1,7%): valtrato e isovaltrato come maggioritari (non sono idrosolubili, sono termolabili e instabili si degradano in baldrinali); alcaloidi (tracce): actinidia, naftiridilmetilcetone; acidi-fenoli; acida y-amino-butirrico; flavonoidi (6-metil-apigenolo, linarina).
La composizione dell' olio essenziale varia secondo la stagione, le condizioni di coltura e soprattutto procedimenti di ottenimento.
La concentrazione in acido valerianico e dei suoi derivati (0,2-0,7%), è massima in marzo (anche 0,9%). La radice fresca è pressoché inodore: durante l'essiccamento compare il tipico odore dovuto alla liberazione dell'acido isovalerianico.
BIBLIOGRAFIA:
- Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats.
K Murphy et al. Phytomedicine. 2010 Jul.
- Enrica Campanini "Dizionario di fitoterapia e piante medicinali".
- Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study. Harshith Chandra Shekhar et al. Adv Ther. 2024 Jan.
- Valeriana officinalis extract and its main component, valerenic acid, ameliorate D-galactose-induced reductions in memory, cell proliferation, and neuroblast differentiation by reducing corticosterone levels and lipid peroxidation. Sung Min Nam et al. Exp Gerontol. 2013 Nov.
- Neuroprotective properties of Valeriana officinalis extracts. João O Malva et al. Neurotox Res. 2004.
- A Review Focused on Molecular Mechanisms of Anxiolytic Effect of Valerina officinalis L. in Connection with Its Phytochemistry through in vitro/in vivo Studies. Ilkay E Orhan. Curr Pharm Des. 2021.
- Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. P D Leathwood et al. Pharmacol Biochem Behav. 1982 Jul.
- Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis. Noriko Shinjyo et al. J Evid Based Integr Med. 2020 Jan-Dec.
- The influence of standardized Valeriana officinalis extract on the CYP3A1 gene expression by nuclear receptors in in vivo model. Anna Bogacz et al. Biomed Res Int. 2014.
- Valeriana officinalis root extract suppresses physical stress by electric shock and psychological stress by nociceptive stimulation-evoked responses by decreasing the ratio of monoamine neurotransmitters to their metabolites. Hyo Young Jung et al. BMC Complement Altern Med. 2014.
- Optimizing the extract yield of bioactive compounds in Valeriana officinalis root: a D-optimal design. Arash Mokhtari et al. Prep Biochem Biotechnol. 2024.
- Effects of Valeriana officinalis (Valerian) on tension-type headache: A randomized, placebo-controlled, double-blind clinical trial. Hossein Azizi et al. Avicenna J Phytomed. 2020 May-Jun.
- Intraspecific Variability of Wild-Growing Common Valerian (Valeriana officinalis L.). Katarzyna Barbara Bączek et al. Plants (Basel). 2022.
- Identification of Nrf2 Activators from the Roots of Valeriana officinalis. Sualiha Afzal et al. Planta Med. 2023 Jan.
- Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [H]Glutamate Binding to Rat Synaptic Membranes. Lisa M Del Valle-Mojica et al. Evid Based Complement Alternat Med. 2011.
- Valeriana officinalis extract and 7-Nitroindozole ameliorated seizure behaviours, and 7-Nitroindozole reduced blood pressure and ECG parameters in pentylenetetrazole-kindled rats. A Kapucu et al. Pol J Vet Sci. 2020 Sep.
- Valeriana officinalis Dry Plant Extract for Direct Compression: Preparation and Characterization. Loreana Gallo et al. Sci Pharm. 2012 Oct-Dec.
- The potential of Valeriana as a traditional Chinese medicine: traditional clinical applications, bioactivities, and phytochemistry. Jianchun Li, Xiaoliang Li, Changfu Wang, Manli Zhang, Minhui Ye, Qiuhong Wang.
- Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties.
Miguel Hattesohl et al. Phytomedicine. 2008 Jan.
- NF-kappaB modulators from Valeriana officinalis. Nadia J Jacobo-Herrera et al. Phytother Res. 2006 Oct.
- Biological and analytical characterization of two extracts from Valeriana officinalis. Clara Circosta et al. J Ethnopharmacol. 2007.
© Copyright Associazione capra&cavoli, condividi non copiare. Grazie
